Epidemiologic and Genomic Investigation of Sexually Transmitted Shigella sonnei, England.

ABSTRACT: Shigellosis is a bacterial infection that causes enteric illness and can be sexually transmitted, particularly among gay, bisexual, and other men who have sex with men. Multiple extensively drug-resistant Shigella strains have been detected through genomic surveillance and are associated with plasmids carrying the gene variant bla_CTX-M-27 in the United Kingdom. We report an increase in possible sexually transmitted cases of Shigella bacteria carrying the bla_CTX-M-15 gene variant, which was previously associated with travel. In 2023, there were 117 cases belonging to the 10 single-nucleotide polymorphism linkage cluster t10.1814. Although this cluster has been documented in England since August 2019, genetic analyses revealed that the bla_CTX-M-15 gene varian

SUBMITTER: Charles H 

PROVIDER: S-EPMC12205470 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature