Natural allelic variation of basic helix-loop-helix transcription factor 25 regulates carotenoid biosynthesis in sweet potato.

ABSTRACT: Carotenoid-rich orange-fleshed sweet potato (OFSP) is an important staple diet and source of nutrition in developing countries, including Africa and Asia. However, the regulation of carotenoid biosynthesis remains to be better understood. A natural allelic variation closely linked to carotenoid biosynthesis was identified in the promoter region of the IbbHLH25 gene that encodes a basic helix-loop-helix (bHLH) transcription factor, by transcriptome and haplotype analyses of different flesh colour sweet potato accessions. An 86-bp deletion reduced the transcription of the IbbHLH25 promoter in white- and yellow-fleshed sweet potatoes; however, the deletion was absent in OFSP. IbbHLH25 was highly expressed in the storage roots of carotenoid-rich sweet potato. The overexpression of IbbHLH25 sig

SUBMITTER: Wei Z 

PROVIDER: S-EPMC12205876 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature