Independent Impacts of Maltreatment and Amygdala Volume on Worsening Callous-Unemotional Traits in High-Risk Youths.

ABSTRACT: Callous-unemotional traits are a major risk factor for aggression and other externalizing behaviors. These traits frequently co-occur with maltreatment exposure, and both of these variables have been independently linked to changes in amygdala structure and function. However, relatively little research has explored how trauma exposure and amygdala structure and function combine to shape callous-unemotional traits. We assessed maltreatment exposure and callous-unemotional traits at two timepoints in children and adolescents who were aged 8-16 years at baseline (54.37% Male, 45.63% Female). We also used magnetic resonance imaging (MRI) to assess amygdala volume and activation in a subset of these youths at baseline (N = 161) and 18 months later (N = 117) using both linear and non-linear appr

SUBMITTER: Berluti K 

PROVIDER: S-EPMC12206202 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature