Impact of smoking status at diagnosis on oncological outcomes of upper-tract urothelial carcinoma.

ABSTRACT:

Background

The evidence supporting personalized surveillance strategies for upper-tract urothelial carcinoma (UTUC) remains limited. This study seeks to explore how smoking habits influence the oncological outcomes of UTUC.

Methods

Data on disease characteristics from UTUC patients were gathered prospectively. Recurrence-free survival was the primary outcome measured. Patients were stratified based on smoking status for Kaplan-Meier and multivariable Cox regression analyses.

Results

A total of 1952 patients were involved, including 684 (35%) patients who never smoked, 572 (29%) that were ex-smokers, and 696 (36%) that were current smokers. For female patients, most of them were nonsmokers (n = 328). Current smokers were significantly younger and had higher Amer

SUBMITTER: Zhao H 

PROVIDER: S-EPMC12206271 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature