Bioactivity Profiling of Chemically Characterized Extract of Saudi Jackfruit (<i>Artocarpus heterophyllus</i>) Using In Vitro and In Silico Approaches.

ABSTRACT: Artocarpus heterophyllus, also known as jackfruit, is recently introduced for cultivation in Saudi Arabia. In this study, the ethanolic extract of Artocarpus heterophyllus fruits (EAHF) was explored for its chemical and pharmacological properties. The EAHF was revealed with total phenolic contents (115.5 ± 5 mg GA.Eq.gm^-1 DE), total flavonoid contents (77 ± 2.22 mg QU.Eq.gm^-1 DE), and total tannin contents (59.33 ± 1.66 mg TA.Eq.gm^-1 DE), while 81 phytocompounds were identified by the GC-MS analysis. The extract was found with maximum antioxidant activity in the FRAP method. EAHF showed significant thrombolytic (85.51%) and hemolytic (1.01%) activities. EAHF showed strong enzyme inhibition, against urease (95.65%), tyrosinase(71.01%), and α-am

SUBMITTER: Aati HY 

PROVIDER: S-EPMC12206570 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature