Electron interaction with laser-desorbed thymidine and guanine in the gas phase.

ABSTRACT:

Abstract

In the present study we investigated electron attachment to the nucleoside thymidine (Td) and the nucleobase guanine (G) using a laser desorption source to transfer the compounds into the gas phase. Previous studies with Td indicated that the compound is thermally labile and may degrade upon thermal heating in standard molecular beam source. The present negative ion mass spectra for laser-desorbed Td and resistively heated Td share the same most three abundant fragment anions. Among those is the dehydrogenated parent anion (Td-H)^- which is strongly enhanced for laser-desorbed Td. We also find a considerable change of the fragmentation pattern for less abundant peaks in the mass spectra as well as changed characteristic in the total and mass selected anion effici

SUBMITTER: Parida D 

PROVIDER: S-EPMC12208974 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature