Impact of the PI-QUAL MRI quality score on histopathological up-staging from MRI fusion biopsy to final prostatectomy specimen.

ABSTRACT:

Purpose

The qualitative heterogeneity of multiparametric MRI (mpMRI) poses significant challenges for the diagnostic pathway of prostate cancer (PCa). The Prostate Imaging Quality Score (PI-QUAL) is a novel tool for the qualitative assessment of mpMRI. Aim of this study was to evaluate the impact of PI-QUAL on consistency of radiological to pathological T-stage.

Methods

Patients undergoing MRI-TRUS fusion biopsy and radical prostatectomy (RP) from 01/2016 to 03/2024 were retrospectively included. PI-QUAL was determined by two expert radiologists and categorised: inadequate (1-2), sufficient (3) and optimal (4-5). Primary endpoint was upstaging from locally confined disease in mpMRI (mrT ≤ 2) to advanced in RP-specimen (pT ≥ 3a). Variables were compared using analysis of vari

SUBMITTER: Haack M 

PROVIDER: S-EPMC12208975 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature