Containment of a carbapenem-resistant <i>Klebsiella pneumoniae</i> in an intensive care unit during the COVID-19 pandemic.

ABSTRACT:

Background

A nosocomial outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP) occurred in the 20-bed Respiratory Intensive Care Unit (RICU) of a tertiary teaching hospital during the COVID-19 pandemic (December 2022-February 2023). The outbreak was ultimately mitigated through multimodal infection control interventions aligned with WHO multidrug-resistant organism (MDRO) management guidelines.

Methods

Following index case identification on 10 December 2022, a multidisciplinary outbreak response team implemented comprehensive control measures: Immediate geographic cohorting of CRKP-positive patients with dedicated staff; Enhanced contact precautions including daily chlorhexidine bathing; Tri-daily environmental decontamination using sporicidal agents; Mandatory

SUBMITTER: Li R 

PROVIDER: S-EPMC12209329 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature