Outcome of monochorionic diamniotic twin pregnancy with selective fetal growth restriction and continuous or intermittent absent or reversed end-diastolic umbilical artery flow: international multicenter cohort study.

ABSTRACT:

Objectives

Monochorionic diamniotic (MCDA) twins with selective fetal growth restriction (sFGR) and either continuous (cAREDF) or intermittent (iAREDF) absent or reversed end-diastolic flow in the umbilical artery face significant fetal and neonatal risks. This study evaluated fetal and neonatal outcomes in these cases and compared outcomes for the larger twin following selective reduction (SR) vs expectant management (EM).

Methods

This was an international retrospective cohort study of MCDA twin pregnancies with sFGR and cAREDF or iAREDF from five fetal medicine centers over 7 years (2016-2022). Patients were included based on an estimated fetal weight (EFW) discordance of ≥ 20% combined with cAREDF or iAREDF. We collected demographic and antenatal characteristics, longitud

SUBMITTER: Noll ATR 

PROVIDER: S-EPMC12209694 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature