Antibiotic use attributable to RSV infections during infancy-an international prospective birth cohort study.

ABSTRACT:

Background

Early-life antibiotic use impacts microbiome composition and contributes to the emergence of antimicrobial resistance. Despite respiratory syncytial virus (RSV) being a leading cause of acute respiratory infections (ARI), accurate estimates of antibiotic use attributable to RSV are lacking.

Objectives

To assess RSV-associated antibiotic use during the first year of life.

Patients and methods

The RESCEU birth cohort study followed healthy term infants, born (n = 9154) between 1 July 2017 and 31 July 2020 from five European countries, to identify RSV-ARI hospitalizations during infancy. In a nested cohort (n = 993), we performed active RSV surveillance by collecting nasal swabs in case of ARI symptoms during RSV seasons (October-April). Antibiotic use during

SUBMITTER: Hak SF 

PROVIDER: S-EPMC12209840 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature