Comparative transcriptome analysis reveals various host responses to sacbrood virus infection in Apis cerana and Apis mellifera.

ABSTRACT: Sacbrood virus (SBV), which infects honey bee larvae and causes significant mortality, represents a serious threat to bee populations and the beekeeping industry. SBV affects both Apis mellifera and Apis cerana, designated according to the host and genotype (AmSBV-AM and AcSBV-AC); however, A. cerana experiences higher mortality rates compared to A. mellifera. Additionally, cross-infections have been observed in both bee species. The genetic regulatory mechanisms involved in infected larvae remain largely unexplored. This study aims to investigate the molecular differences in the responses of A. cerana infected with AcSBV-AC and A. mellifera infected with AmSBV-AM. The results demonstrated significant differences in the expression patterns of differentially expressed genes (DEGs) between t

SUBMITTER: Chang ZT 

PROVIDER: S-EPMC12210461 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature