Association of SNPs in carbohydrate metabolism genes with insulin resistance indicators in the Mexican population.

ABSTRACT:

Introduction

Insulin resistance (IR) is a key feature in the pathophysiology of metabolic disorders such as type 2 diabetes mellitus (T2DM) and obesity, both of which have a high prevalence in the Mexican population. Genetic predisposition plays a critical role in the development of IR, particularly through variants in carbohydrate metabolism genes. However, the specific contributions of these genetic factors in young Mexicans remain poorly characterized.

Objectives

This study aimed to identify associations between single nucleotide polymorphisms (SNPs) in carbohydrate metabolism-related genes and insulin resistance markers in a young Mexican population. Additionally, we sought to identify novel genetic variants that may contribute to metabolic risk and explore sex-specific

SUBMITTER: Mendez-Garcia A 

PROVIDER: S-EPMC12210724 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature