Physicochemical, genomic, and phenotypic characterization of <i>Escherichia</i> phage BME3.

ABSTRACT: Infections caused by pathogenic Escherichia coli strains are increasing, and with the rising of antimicrobial resistance among bacterial pathogens, alternative therapeutic options are being actively explored, including phage therapy. In this research, a new bacteriophage, provisionally named BME3, with lytic activity against Escherichia coli was identified and characterized at the physicochemical, morphological, and genetic levels. BME3 was isolated from the tropical estuarine waters of Estero Salado, Guayaquil, Ecuador. Subsequently, it was purified and amplified, followed by a series of tests that included host range, stability studies, morphological characterization by transmission electron microscopy (TEM), and whole genome sequencing. The genomic analysis revealed that B

SUBMITTER: Toaquiza-Vilca B 

PROVIDER: S-EPMC12210895 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature