Comparative genomic analysis of <i>Escherichia coli</i> isolated from cases of bovine clinical mastitis and the dairy farm environment.

ABSTRACT: Escherichia coli is a major causative agent of environmental bovine mastitis, and this disease causes significant economic losses for the dairy industry. There is still debate in the literature as to whether mammary pathogenic E. coli (MPEC) is indeed a unique E. coli pathotype or if this infection is merely an opportunistic infection caused by any E. coli isolate being displaced from the bovine gastrointestinal tract to the environment and then into the udder. In this study, we conducted a thorough genomic analysis of 113 MPEC isolates from clinical mastitis cases and 100 environmental E. coli isolates from the environment of dairy farms around the world. A phylogenomic analysis indicated that MPEC and the environmental E. coli isolates formed cla

SUBMITTER: Jung D 

PROVIDER: S-EPMC12211228 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature