An insight into the draft genome of the Oriental rat flea, Xenopsylla cheopis, together with its Wolbachia endosymbiont.

ABSTRACT:

Background

The Oriental rat flea, Xenopsylla cheopis, is a main vector of plague caused by the bacterium Yersinia pestis. Transcriptomic analysis of this insect and the interaction between Yersinia and the flea digestive tract have been the subject of several studies. However, to develop more refined studies on this vector in the future, we sequence and describe a draft genome of the rat flea Xenopsylla cheopis, discuss the physiological implications of its genetic features, and compare them with the only other sequenced member of the Siphonaptera, the cat flea, Ctenocephalides felis.

Results

Sequencing data from both long and short reads were assembled into 7,694 contigs, from which 95,638 putative coding sequences (CDSs) were extracted and functionally annotated, providing

SUBMITTER: Lu S 

PROVIDER: S-EPMC12211885 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature