Palliative radiotherapy in symptomatic pelvic soft tissue tumors (PallSoft)- protocol for a national, randomized, non-inferiority study.

ABSTRACT:

Background

Palliative radiotherapy is essential in the management of patients with symptomatic pelvic soft tissue tumors, often providing rapid and efficient symptom relief. No standard treatment recommendations currently exist, yielding large differences in patient management across cancer types and institutions. PallSoft is a national, phase III, non-inferiority study aiming to compare two short-course radiotherapy approaches for these patients.

Methods

200 patients will be recruited from 11 institutions over 2-4 years. Patients with either gastrointestinal, urological or gynecological cancers, referred to palliative radiotherapy due to a symptomatic pelvic soft tissue tumor, are eligible for study inclusion. Patients will define their target symptom and be randomly assign

SUBMITTER: Skipar K 

PROVIDER: S-EPMC12211963 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature