A prospective cluster randomized trial of an interventions bundle to reduce inappropriate antibiotic use for upper respiratory tract infections in the outpatient setting.

ABSTRACT:

Background

Antibiotic overuse and increasing antimicrobial resistance are global public health threats. We determined the impact of a multicomponent intervention in reducing inappropriate antibiotic use for upper respiratory tract infections (URTIs) in the outpatient setting.

Methods

DESIGN: Prospective, cluster-randomized trial.

Intervention

Bundled 4-component intervention including extensive provider education, a decision support algorithm, option for deferred antibiotics prescription, and monthly feedback on prescription patterns, vs. a single randomly assigned intervention (decision support algorithm).

Setting

Four Primary healthcare centers in Qatar with study period from August 2023 to October 2024.

Participants

Individuals with a diagnosis of URT

SUBMITTER: Butt AA 

PROVIDER: S-EPMC12211981 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature