Cardiopulmonary exercise testing parameters in healthy athletes vs. equally fit individuals with hypertrophic cardiomyopathy.

ABSTRACT:

Aims

Cardiopulmonary exercise testing (CPET) is often used when athletes present with suspected hypertrophic cardiomyopathy (HCM). While low peak oxygen consumption (pV˙O2) augments concern for HCM, athletes with HCM frequently display supranormal pV˙O2, which limits this parameter's diagnostic utility. We aimed to compare other CPET parameters in healthy athletes and equally fit individuals with HCM.

Methods and results

Using cycle ergometer CPETs from a single centre, we compared ventilatory efficiency and recovery kinetics between individuals with HCM [percent predicted pV˙O2(ppV˙O2) > 80%, non-obstructive, no nodal agents] and healthy athletes, matched (2:1 ratio) for age, sex, height, weight and ppV˙O2. Consistent with matching, HCM (n = 30, 43.6 ± 14.2 years) and athle

SUBMITTER: McHugh C 

PROVIDER: S-EPMC12212187 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature