Functional connectivity and GABAergic signaling modulate the enhancement effect of neurostimulation on mathematical learning.

ABSTRACT: Effortful learning and practice are integral to academic attainment in areas like reading, language, and mathematics, shaping future career prospects, socioeconomic status, and health outcomes. However, academic learning outcomes often exhibit disparities, with initial cognitive advantages leading to further advantages (the Matthew effect). One of the areas in which learners frequently exhibit difficulties is mathematical learning. Neurobiological research has underscored the involvement of the dorsolateral prefrontal cortex (dlPFC), the posterior parietal cortex (PPC), and the hippocampus in mathematical learning. However, their causal contributions remain unclear. Moreover, recent findings have highlighted the potential role of excitation/inhibition (E/I) balance in neuroplasticity and l

SUBMITTER: Zacharopoulos G 

PROVIDER: S-EPMC12212564 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature