Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.

ABSTRACT:

Background

Evidence connecting mean arterial pressure (MAP) with impaired fasting glucose (IFG) was currently insufficient. The purpose of our research was to investigate how age and sex individually affect the relationship between MAP and the onset of IFG.

Methods

Our study was a retrospective cohort analysis involving 184,291 participants from a multicenter health examination in China. The relationship between MAP and the onset of IFG was evaluated using Cox regression analysis. To further investigate the relationship, smooth curve fitting was applied to evaluate the dose-response association, while threshold effect analysis was performed to identify potential inflection points in MAP. Additionally, interaction effect analysis was conducted to examine whether age and sex m

SUBMITTER: Lin Y 

PROVIDER: S-EPMC12213370 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature