Do 3D-Printed and Milled Denture Bases Differ in Microbial Activity and Adhesion? A Systematic Review and Meta-Analysis.

ABSTRACT: The increasing adoption of digital manufacturing in prosthodontics raises concerns about microbial metabolic activity and adhesion on denture bases fabricated via additive and subtractive methods. This systematic review aimed to compare microbial metabolic activity and microorganism adhesion between 3D-printed and milled complete denture bases. A systematic search of PubMed, Scopus, Web of Science, Embase, and the Cochrane Library was conducted up to December 2024. Studies were screened according to predefined eligibility criteria, and data were independently extracted by two reviewers. The standardized mean difference (SMD) was used to compare microbial metabolic activity and cell adhesion outcomes between groups. A random-effects model was applied for meta-analysis, and heterogeneity was

SUBMITTER: Arzani S 

PROVIDER: S-EPMC12214270 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature