A sensation driven functional MRI study on brain activation during bladder filling in healthy participants.

ABSTRACT: Understanding the central control of bladder perception is important to comprehend the neurophysiological mechanism behind bladder sensation and lower urinary tract dysfunction. Here we design a sensation-driven functional magnetic resonance imaging (fMRI) during repetitive bladder filling and examine brain activation related to the first desire to void (FDV) and strong desire to void (SDV) sensations. These sensations are subjective and can be transient, making their study particularly challenging and insightful. To prevent constant engagement of the viscerosensory cortex and to add a layer of complexity, a diversion continuous performance task (CPT) was randomly presented. We modelled and analysed the data given the recorded responses and assessed the validity and reliability of our para

SUBMITTER: Santoso AD 

PROVIDER: S-EPMC12214491 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature