Impact of rehabilitation on quality of life in patients with degenerative cerebellar ataxias using structural equation modeling.

ABSTRACT: Degenerative cerebellar ataxias (DCAs) are progressive diseases that reduce quality of life (QoL). This study aimed to assess the impact of rehabilitation on QoL in patients with DCAs using structural equation modeling (SEM). This cross-sectional survey included members of a national Japanese DCAs patient association. Assessed latent variables included personal, medical, and environmental factors, impairments, activity limitations, rehabilitation (participation quantity and patient-reported quality), and QoL. SEM was used to explore causal relationships between these latent variables. Overall, 477 participants (mean age 65.4 years; 45.1% female) were included. Impairments were categorized as primary and secondary, based on preliminary analyses. The final model demonstrated acceptable-to-go

SUBMITTER: Haruyama K 

PROVIDER: S-EPMC12214628 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature