Evolution of mitochondrial RNA editing sites and stop codon-lacking transcripts in angiosperms.

ABSTRACT: While the evolution of mitochondrial protein-coding genes in angiosperms has been extensively studied, the post-transcriptional RNA processing remains under-explored. Leveraging newly generated and public RNA-seq data from twenty representative angiosperms, we systematically inferred the gain-and-loss dynamics of RNA editing sites within mitochondrial protein-coding genes. Our findings reveal magnoliids retain more ancestral RNA editing sites compared to monocots and eudicots. Furthermore, we uncovered contrasting correlations between gene expression levels and RNA editing density: negative in core mitochondrial genes but positive in variable genes. We also identified widespread occurrence of stop codon-lacking transcripts of four genes (ccmC, nad6, sdh3 and sdh4) across angiosperms, a phe

SUBMITTER: Yu R 

PROVIDER: S-EPMC12214727 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature