Cerebral Saturation and Fractional Tissue Oxygen Extraction Are Associated with Anterior Cerebral Artery Doppler Parameters in Neonates with Congenital Heart Defects.

ABSTRACT:

Introduction: The aim of the study was to explore the relationship between near-infrared spectroscopy parameters (cerebral saturation [CSat] and corresponding cerebral fractional tissue oxygen extraction [cFTOE]) with resistive (RI) and pulsatility indices (PI) of the anterior cerebral artery (ACA) obtained simultaneously in neonates with congenital heart defect (CHD) during the first week of life.

Methods

Prospective observational study on neonates ≥35 weeks with CHD was conducted. Cerebral FTOE was based on concomitant pre-ductal oxygen saturation (SpO₂) during CSat measurement. ACA was assessed via Doppler ultrasound (US). Continuous CSat/SpO₂ monitoring was collected during the first week of life. Daily ACA Doppler was obtained from day 1-7.

Results</

SUBMITTER: Kanaprach P 

PROVIDER: S-EPMC12215159 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature