The efficacy of mosapride on recovery of intestinal motility after elective colorectal cancer surgery: a randomized controlled trial.

ABSTRACT:

Purpose

Postoperative ileus is the physiologic hypomotility of the gastrointestinal tract that occurs immediately after abdominal surgery. Mosapride citrate is known to enhance gastrointestinal motility. This study aimed to evaluate mosapride's impact on postoperative ileus and gastrointestinal motility in patients undergoing elective colorectal surgery.

Methods

Forty-four patients with colorectal cancer undergoing surgery at Ramathibodi Hospital between July 2021 and August 2022 were randomly assigned to either a mosapride group or a control group. The mosapride group received 5 mg of mosapride via the enteric route with 50 mL of water 3 times daily, beginning on postoperative day 1, while the control group received 5 mg of a placebo with 50 mL of water on the same schedule

SUBMITTER: Thampongsa T 

PROVIDER: S-EPMC12215320 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature