Increased risk of lung cancer in individuals with preserved ratio impaired spirometry: a nationwide cohort study.

ABSTRACT: Accumulating data showed that individuals with preserved ratio impaired spirometry (PRISm) have an increased risk for all-cause mortality and respiratory-related mortality compared with normal spirometry. However, the association between PRISm and lung cancer development is not known. A retrospective cohort study was conducted using the Korean National Health and Nutrition Examination Survey data between 2007 and 2017, which was linked to the Health Insurance Review and Assessment database from 2007 to 2021. Men and women aged 40 to 79 years were categorized by baseline spirometry; PRISm (FEV₁/FVC ≥ 0.7 and FEV₁ < 80% pred), COPD (FEV₁/FVC < 0.7) and normal spirometry (FEV₁/FVC ≥ 0.7 and both FEV₁ and FVC ≥ 80% pred). Incident lung can

SUBMITTER: Kim T 

PROVIDER: S-EPMC12216650 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature