Risk Factors for Serrated Polyps: Results From a Large, Multicenter Colonoscopy-Based Study.

ABSTRACT:

Introduction

Risk factors for serrated polyps (SPs) are not well understood.

Methods

Multivariable analyses of data from a multicenter colonoscopy-based study estimated odds ratios for having either a sessile serrated lesion or traditional serrated adenoma according to participant characteristics.

Results

Six thousand seventy-eighty participants were included in the analyses (565 with either a sessile serrated lesion or traditional serrated adenoma). White race was associated with a higher risk of SPs compared with Black race (adjusted odds ratio 4.64, 95% confidence interval 1.89-11.41). Obesity and current smoking were also associated with a higher risk of SPs.

Discussion

White race, smoking, and obesity are risk factors for precancerous SPs.

SUBMITTER: Crockett SD 

PROVIDER: S-EPMC12217339 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature