Detection of bovine leukemia virus, Epstein-Barr virus and human papillomavirus in breast cancer tissues of Egyptian patients.

ABSTRACT:

Background

Breast cancer (BC) remains one of the most common malignancies worldwide. Many viruses have been linked to BC; namely, Human papillomavirus (HPV), Epstein-Barr virus (EBV) and Bovine leukemia virus (BLV). However, a causal role is yet to be established.

Objectives

To detect the prevalence of BLV, EBV and HPV sequences in BC tissue compared to BC-free tissue and correlate their presence with different pathological features of BC.

Subjects and methods

A retrospective case-control study was conducted on 75 FFPE (formalin fixed paraffin embedded) blocks of BC tissues and 25 of BC-free tissues obtained from Alexandria Main University Hospital pathology department archive. Demographic, medical, pathological data were retrieved from patients' archival records. Hor

SUBMITTER: Raouf M 

PROVIDER: S-EPMC12218089 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature