Parenteral viral hepatitis among students in Da Nang, Vietnam, and insights into new hepatitis B virus genotype B classification.

ABSTRACT: This cross-sectional study estimated the prevalence of hepatitis B, C, D viruses among adults aged 18-22 years and assessed the impact of viral populations on the epidemiological trends in hepatitis virus transmission. A total of 568 students of Da Nang University were enrolled in the study in 2018. The prevalence of HBsAg, anti-HBs and anti-HBc was 4.2% (24/568), 30.4% (173/568), and 17.6% (100/568), respectively. Anti-HCV was found in 0.2% (1/568) of samples, and no participants tested positive for anti-HDV. HBV DNA was detected in all HBsAg-positive samples: 19 HBV isolates belonged to genotype B, and 5-to genotype C. Eight isolates carried immune escape mutations within the S protein, and one harbored three mutations (1762A > T / 1764G > A, 1858 T > C) in the precore/core region. Most

SUBMITTER: Kalinina OV 

PROVIDER: S-EPMC12218278 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature