Human lymph node microvascular imaging using a fast contrast-free super-resolution ultrasound technique.

ABSTRACT: Lymph nodes play a crucial role in cancer metastasis, and assessing lymph node involvement is essential for patient prognosis and treatment strategies. Super-resolution ultrasound imaging (SRUS), including ultrasound localization microscopy (ULM), has shown promise in visualizing the lymph node microvasculature, however, ULM requires microbubbles injection, monitoring, and long acquisition times. This study investigates the feasibility of using a fast contrast-free SRUS approach based on erythrocytes (SURE) to visualize and quantify the microvasculature in human lymph nodes. The SURE pipeline detects and tracks erythrocyte scatterer peaks to generate high-resolution microvascular images with a resolution of less than half the wavelength in 2 seconds of data acquisition. SURE visualized the

SUBMITTER: Amin Naji M 

PROVIDER: S-EPMC12218869 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature