The influence of serotonergic multilocus genetic variants and parent-child relationship on adolescent creativity.

ABSTRACT:

Objective

Creativity drives both individual progress and societal development. With the development of the gene-environment interaction theory, investigating the physiological and psychological mechanisms underlying creativity has become increasingly essential. Grounded in Bronfenbrenner's ecological systems theory, this study employs the gene-environment (G × E) paradigm to investigate the interaction between serotonin system genes and the parent-child relationship in influencing adolescent creativity.

Methods

In study 1, questionnaire surveys and DNA genotyping techniques were used to select a sample of 707 middle school students (Mage = 13.95, SD = 0.42). The 5-HT MGPS was constructed by including TPH2 rs4570625, SLC6A4 rs1042173, 5-HTR1A rs6295, and MAOA rs6323 genes to

SUBMITTER: He Z 

PROVIDER: S-EPMC12219562 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature