Mutations of the complex I PSST target gene confers acaricide resistance and a fitness cost in Panonychus citri.

ABSTRACT:

Background

Pesticide resistance is a serious problem that threatens crop industries. Major resistance towards pyridaben, an acaricidal inhibitor of mitochondrial electron transport complex I (METI-Is), has been reported in tetranychids following its extensive use worldwide. Understanding mechanisms of pyridaben resistance is crucial for sustainable resistance management.

Results

The inheritance of pyridaben resistance was incompletely recessive and controlled by multiple genes in P. citri, which was determined by reciprocal crosses and backcross experiments. Bulked segregant analysis was performed to identify gene loci underlying pyridaben resistance. Subsequently, the two PSST-subunit mutations H107R and the previously undiscovered V103I mutation were positively correlated

SUBMITTER: Pan D 

PROVIDER: S-EPMC12220261 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature