Comprehensive analysis of SPL gene family and miR156a/SPLs in the regulation of terpenoid indole alkaloid biosynthesis in Catharanthus roseus L.

ABSTRACT:

Background

Catharanthus roseus (C. roseus), belongs to the dogbane family Apocynaceae, is the source of various terpenoid indole alkaloids (TIAs) with excellent antitumor properties, including vinblastine, vincristine, ajmalicine, serpentine, vindoline, and catharanthine. However, TIAs are widely used in clinical anticancer research, their content is extremely low in plants, and currently insufficient to meet market demand. Therefore, exploring TIAs regulation is essential to improve TIAs yield. Numerous transcription factors have been shown to be involved in vinblastine biosynthesis, while the function of SPL members (CrSPL) has not yet been investigated in C. roseus. SPL genes regulate both plant growth and development as well as metabolite accumulation.

Results

In this st

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12220395 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature