Comparative analysis of cryoballoon versus radiofrequency catheter ablation in atrial fibrillation patients with impaired left ventricular ejection fraction.

ABSTRACT:

Background

In selected patients with atrial fibrillation (AF) and impaired left ventricular ejection fraction (LVEF), catheter ablation has been proposed for rhythm control. It is unclear, if cryoballoon (CBA) or radiofrequency (RFA) ablation is the preferred technique.

Methods

The FREEZE Cohort (NCT01360008) sub-analysis included patients with LVEF < 50 % undergoing CBA (Group A) or RFA (Group B) comparing baseline characteristics, procedural data and outcome.

Results

From 2011 to 2016; 4,189 patients were enrolled, with 256 (6.1 %) qualifying for the sub-analysis and divided into two groups: 118 (Group A) and 138 (Group B). Mean age was 63.4 ± 9.9 years (p = 0.07), with 60.9 % suffering from persistent AF (p = 0.46). Mean LVEF was 42.0 % (p = 0.81). CHA₂D

SUBMITTER: Pongratz J 

PROVIDER: S-EPMC12221379 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature