FLIP use in achalasia: comparing POEM and Heller myotomy outcomes: a systematic review and meta-analysis.

ABSTRACT:

Background

Achalasia is a debilitating esophageal motility disorder characterized by absent peristalsis and incomplete relaxation of the lower esophageal sphincter (LES). Myotomy procedures-primarily peroral endoscopic myotomy (POEM) and laparoscopic Heller myotomy (LHM)-aim to reduce LES pressure and alleviate dysphagia. The functional lumen imaging probe (FLIP) measures real-time changes in esophagogastric junction (EGJ) compliance and distensibility during myotomy. We conducted a systematic review and meta-analysis of peer-reviewed literature on the use of preprocedural and intraprocedural FLIP in guiding myotomy adequacy and their impact on clinical outcomes.

Methods

We conducted a systematic review and meta-analysis adhering to PRISMA and Cochrane guidelines. Literature

SUBMITTER: Alabbas M 

PROVIDER: S-EPMC12222239 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature