Building a growing genomic repository for maternal and fetal health through the PING Consortium.

ABSTRACT:

Background

Prenatally transmitted viruses can cause severe damage to the developing brain. There is unexplained variability in prenatal brain injury and postnatal neurodevelopmental outcomes, suggesting disease modifiers. Of note, prenatal Zika infection can cause a spectrum of neurodevelopmental disorders, including congenital Zika syndrome. Currently, there is no preventative treatment or cure. The Prenatal Infection and Neurodevelopmental Genetics (PING) Consortium aims to identify modulators of brain injury and adverse neurodevelopmental outcomes for Zika and other prenatal viral infections.

Methods

The Consortium pools information from eight multi-site studies conducted at 23 research centers in six countries to build a growing clinical and genomic repository, which is

SUBMITTER: Abdelmalek CM 

PROVIDER: S-EPMC12222536 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature