Biomarkers for intensive care unit-acquired weakness: a systematic review for prediction, diagnosis and prognosis.

ABSTRACT:

Background

Intensive care unit-acquired weakness (ICU-AW) is a common and debilitating complication in critically ill patients, significantly affecting both short- and long-term outcomes. The existing ICU-AW diagnostic methods are not widely accepted and have a narrow application window. Biomarkers offer potential for diagnosing, predicting, and prognosticating ICU-AW, but a comprehensive synthesis of the available evidence is still lacking.

Methods

We conducted a systematic search across PubMed, Cochrane Library, Embase, Web of Science, CNKI, Wanfang Database, China Science and Technology Journal Database (VIP Database), and China Biomedical Literature Database (SinoMed Database) from inception to January 23, 2025. Study quality was assessed using the revised Newcastle-Otta

SUBMITTER: Song J 

PROVIDER: S-EPMC12222590 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature