Morphologic characteristics of distal intracranial arteries in relation to structural changes in the brain after chronic alcohol consumption.

ABSTRACT: This study focuses on the structural brain changes, alterations in Apparent Diffusion Coefficient (ADC) values, and the morphological characteristics of distal intracranial arteries in chronic alcohol consumption. A total of 50 chronic alcoholics and 43 non-alcoholics were recruited from neurology inpatient and outpatient services. Using the Brainnetome Atlas to segment the brain into 246 regions, ADC values were observed to be consistently higher in alcoholics, with statistically significant differences in 134 of these regions. This number is far greater than the number of brain regions where changes in gray matter volume were observed. The alcohol group exhibited lower mean arterial density, mean arterial radius, and mean arterial tortuosity, along with higher mean arterial flexibility,

SUBMITTER: Wang C 

PROVIDER: S-EPMC12223039 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature