Systematic analysis of population studies performed with the ForenSeq™ DNA Signature Prep kit.

ABSTRACT: Many forensic laboratories have conducted sequence-based population studies to support the integration of massively parallel sequencing (MPS). However, the data remain limited concerning African populations. MPS enhances allelic representation compared to CE methods. It is hypothesized that this increase will be more pronounced for African populations due to their greater genetic diversity. A systematic review and meta-analysis were conducted to compile data from population genetic studies using the ForenSeq™ DNA Signature Prep kit, frequently employed in forensic MPS population studies. The aim of the review was to gain insight into global forensic sequence-based population data, focusing on African and underrepresented populations. The search spanned three databases, resulting in 582 rec

SUBMITTER: Martin DP 

PROVIDER: S-EPMC12223351 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature