Cyanoglobule lipid droplets are a stress-responsive metabolic compartment of cyanobacteria and the progenitor of plant plastoglobules.

ABSTRACT: Lipid droplets (LDs) are well integrated into multiple facets of cellular physiology and potentially represent an effective platform for engineering heterologous metabolic pathways. LDs of chloroplasts, known as plastoglobules, mediate stress tolerance through dynamic and reversible changes to morphology and molecular composition. However, the dynamics and functional role(s) of cyanobacterial LDs are almost wholly unknown. Here, we have characterized the morphological behavior and quantitative proteome and lipidome of cyanobacterial LDs of Synechocystis sp. PCC 6803 grown under permissive or phosphorous-deficient media for 7 d. Our results show that cyanobacterial LDs are a metabolically active subcompartment of cyanobacteria with dynamic morphology and composition. The cyanobacterial LD p

SUBMITTER: Susanto FA 

PROVIDER: S-EPMC12223511 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature