Enhanced Antimicrobial and Biofilm-Disrupting Properties of Gallium-Doped Carbon Dots.

ABSTRACT: Antibiotic resistance continues to be a global health threat caused by microbial biofilms, yet carbon dots (CDs) offer a promising countermeasure. Doping CDs with metals or nonmetals further enhances their properties while maintaining biocompatibility. This work reports the sonochemical synthesis of gallium-boronic acid carbon dots (Ga-BACDs) under conditions (20 kHz, 2000 W, 60% amplitude, 60 °C, and 60 min), achieving significant gallium incorporation. Ultraviolet-visible and fluorescence analyses reveal characteristic CD absorbance peaks at 286 and 355 nm and strong emission at 397-400 nm. Fourier transform infrared spectral changes on Ga-BACDs suggest successful incorporation of gallium and confirm Ga-H/Ga-O-C (2000-2600 cm^{- 1}) and Ga-O/Ga-O-Ga (400-700 cm^-</

SUBMITTER: Radha R 

PROVIDER: S-EPMC12223810 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature