Flexible Neural Probe with an Optimized Electrode Density for Neutral Investigations.

ABSTRACT: Neural probes are essential tools for the study of neural networks and brain function. While silicon-based probes offer high-electrode density and precise recordings, their high fabrication cost and complex packaging requirements limit scalability and accessibility. Flexible neural probes utilizing flexible printed circuit board (FPCB) technology have emerged as a cost-effective alternative, but their low electrode density, attributed to process limitations, remains a challenge. Herein, we present a fabrication-optimized, flexible neural probe with enhanced electrode density. By optimizing line width and spacing, we considerably increased electrode density while maintaining compatibility with standard FPCB processes. A stiffener layer was incorporated to improve substrate planarity, and a

SUBMITTER: Park S 

PROVIDER: S-EPMC12223837 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature