Comprehensive Characterization and Biological and Safety Evaluation of Zinc Oxide-Curcumin Nanoconjugates: Unraveling Synergistic Effects for Enhanced Therapeutic Applications.

ABSTRACT: Nanoparticles have been widely synthesized and used in various biological applications. Among the minerals, zinc (Zn) alters numerous biological pathways, and curcumin (Cur) functions mainly as the antimicrobial, anti-inflammatory, and anticancerous agent. In this study, nano-zinc oxide (nZnO), nano-curcumin (nCur), and its conjugate (nZnOcur) were synthesized through the chemical reduction method. The particles were characterized using UV-visible (UV-visible) spectroscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDS), high-resolution transmission electron microscopy (HR-TEM), dynamic light scattering (DLS), and ζ-potential measurements. The UV-visible spectrum revealed that nZnO had an

SUBMITTER: Rajendran D 

PROVIDER: S-EPMC12223860 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature