ROS-Specific Neutralization of Bioactive Compounds: An Optical Approach.

ABSTRACT: Reactive oxygen species (ROS) are partially reduced or excited forms of oxygen as byproducts of aerobic metabolism (endogenous sources). When cellular redox homeostasis is chronically affected by ROS overproduction or insufficient antioxidant activity (i.e., oxidative stress), different pathologies develop as a result of inflammation. Bioactive antioxidant compounds have been widely used to counter oxidative stress. However, the analytical methods available to explore their ROS scavenging capacity do not allow a comparison between different ROS species for a compound. In this work, we present an optical approach to evaluate the ROS-specific neutralization capacity of bioactive compounds as a function of the pH value, carrier system, and synergy among several compounds. We analyzed the prof

SUBMITTER: Buenfil-Chi TJ 

PROVIDER: S-EPMC12224101 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature