Evaluation of the Effects of Sumac () Extract-Loaded Ethosomes on an <i>In Vitro</i> Wound Healing Model.

ABSTRACT: Wound healing involves a series of complex bioprocesses, including repairing skin damage, maintaining its barrier features, and preserving all other skin functions. Since the skin is the primary organ exposed to external factors, these bioprocesses can be interrupted by potential exogenous toxicants. Efforts to mitigate the effects of these toxicants can help accelerate the healing process, facilitating complete wound recovery. In this context, sumac () extract, rich in polyphenolics with antioxidant and anti-inflammatory properties, can be exploited to overcome oxidant and inflammation-dependent burdens. Ethosomes, lipid-based intradermal delivery vehicles, have been selected for the delivery of sumac extract, as they enhance penetration through the skin layers. Considering their remarkab

SUBMITTER: Emanet M 

PROVIDER: S-EPMC12224110 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature