Adenomatous Polyposis Coli Gene Mutations, Risk Factors, and Long-term Outcomes Associated With Desmoid Tumors in Patients With Familial Adenomatous Polyposis After Colectomy in Japan.

ABSTRACT:

Goals

To clarify the characteristics of desmoid tumors in Japanese patients with familial adenomatous polyposis after colectomy.

Background

Few comprehensive reports have been published on desmoid tumors in Asian patients with familial adenomatous polyposis.

Study

This retrospective study included the data of 81 patients with familial adenomatous polyposis who underwent surgery between 1978 and 2021. The adenomatous polyposis coli gene mutation sites, risk factors, and long-term outcomes associated with desmoid tumors in Japanese patients with familial adenomatous polyposis after colectomy were analyzed.

Results

No association was observed between the gene mutation sites and desmoid tumor development in 40 patients who underwent genetic analyses. The rate of de

SUBMITTER: Kojima T 

PROVIDER: S-EPMC12225722 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature