Association between post-PCI vessel fractional flow reserve (vFFR) and optical coherence tomography (OCT) findings: Results from the FAST OCT study.

ABSTRACT:

Aims

Reduced post-PCI fractional flow reserve (FFR) and suboptimal optical coherence tomography (OCT) findings are associated with impaired outcomes. Angiography-derived vessel FFR (vFFR) has emerged as an accurate alternative to pressure-wire based FFR. This study sought to define the association between post-PCI vFFR and OCT findings.

Methods and results

The FAST OCT study included 200 patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) and intermediate to severe coronary artery stenosis. Patients with post-PCI OCT and vFFR evaluation of at least one study vessel were included in this post-PCI sub-analysis. Complete post PCI OCT and vFFR data were available for 109 vessels (100 patients). Median post-PCI vFFR was 0.93 [25th-75th percentile 0.90-0.96], median

SUBMITTER: Ziedses des Plantes AC 

PROVIDER: S-EPMC12226037 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature