Intracranial atherosclerotic plaque features on vessel wall imaging predict first ever and recurrence of stroke: a meta-analysis.

ABSTRACT:

Objectives

Intracranial atherosclerotic disease (ICAD) features on vessel wall magnetic resonance imaging (VW-MRI) are associated with first-ever or recurrent ischemic stroke (IS) or transient ischemic attack (TIA). There are multiple longitudinal ICAD VW-MRI studies, but they are limited by small sample size, non-standardized imaging acquisition and analysis, and some controversial results. Hence, we conducted the current meta-analysis of intracranial plaque features predicting recurrence of IS.

Materials and methods

PubMed, Web of Science, and EMBASE databases were searched through March 2024. Two independent reviewers extracted data on study design, VW-MRI techniques, and patient outcome. Quality assessment was used by the NOS tool. Subgroup analyses, sensitivity analysis

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12226209 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature