A randomised controlled trial comparing three clinical administration strategies in spectral detector CT pulmonary angiography with low contrast medium dose.

ABSTRACT:

Objectives

To compare vascular attenuation (VA) with three strategies for administering a low contrast medium (CM) dose in dual-layer spectral detector CT pulmonary angiography (CTPA).

Methods

Patients were prospectively randomised into control- or one of two experimental groups. Control group patients received CM (350 mgI/mL) diluted 1:1 with saline. Experimental group B received CM (350 mgI/mL) with low flow. Experimental group C received CM with low concentration (140 mgI/mL). Virtual monoenergetic images at 40 and 55 kiloelectron Volt (keV) were reconstructed. Objective examination quality (OEQ) i.e., VA, noise, and signal-to-noise ratio, was measured and subjective examination quality (SEQ) was rated at three anatomical levels: in the pulmonary trunk (PT), the interloba

SUBMITTER: Kristiansen CH 

PROVIDER: S-EPMC12226604 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature